Pub. Date : 2002 Sep 13
PMID : 12091394
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Apoptotic changes in the aged brain are triggered by interleukin-1beta-induced activation of p38 and reversed by treatment with eicosapentaenoic acid. | Eicosapentaenoic Acid | interleukin 1 beta | Rattus norvegicus |
| 2 | This study investigated the possibility that treatment with the polyunsaturated fatty acid eicosapentaenoic acid might prevent interleukin-1beta-induced deterioration in neuronal function. | Eicosapentaenoic Acid | interleukin 1 beta | Rattus norvegicus |
| 3 | These changes were coupled with an age-related deficit in long term potentiation in perforant path-granule cell synapses, while eicosapentaenoate treatment was associated with reversal of age-related changes in interleukin-1beta and p38 and with restoration of long term potentiation. | Eicosapentaenoic Acid | interleukin 1 beta | Rattus norvegicus |