Title : [Dihydropyrimidine dehydrogenase and thymidylate synthase in colon carcinoma].

Pub. Date : 2002 Jun

PMID : 12090040






1 Functional Relationships(s)
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1 These results suggest that the reduction of DPD activity is associated with the elevation of TS content, which may be connected with the development of 5-FU resistance and the effectiveness of biochemical modulation through the stabilization of TS inhibition with folic acid in colon carcinoma. Folic Acid dihydropyrimidine dehydrogenase Homo sapiens