Title : Testosterone and estradiol modulate TNF-alpha-induced expression of adhesion molecules in endothelial cells.

Pub. Date : 2002 Apr

PMID : 12087872






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1 Testosterone and estradiol modulate TNF-alpha-induced expression of adhesion molecules in endothelial cells. Testosterone tumor necrosis factor Homo sapiens
2 In the present study, we investigated the influences of testosterone and 17 beta-estradiol on tumor necrosis factor-alpha (TNF-alpha)-induced expression of adhesion molecules in human umbilical vein endothelial cells (HUVEC). Testosterone tumor necrosis factor Homo sapiens
3 In the present study, we investigated the influences of testosterone and 17 beta-estradiol on tumor necrosis factor-alpha (TNF-alpha)-induced expression of adhesion molecules in human umbilical vein endothelial cells (HUVEC). Testosterone tumor necrosis factor Homo sapiens
4 It is concluded that both testosterone and 17 beta-estradiol increase TNF-alpha-induced expression of E-selectin and VCAM-1 in endothelial cells and these facts might indicate a mechanism by which gonadal hormones can indirectly enhance immune responses. Testosterone tumor necrosis factor Homo sapiens