Title : High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.

Pub. Date : 2002 Jun

PMID : 12082016






1 Functional Relationships(s)
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1 Tp53 was also strongly induced by an N-oxide of quinoline and by dabequine, an experimental antimalarial evaluated in humans; dabequine was reported to be negative in other screens of mutagenicity and clastogenicity but carcinogenic in animal studies. quinoline tumor protein p53 Homo sapiens