Title : PPARs: transcription factors controlling lipid and lipoprotein metabolism.

Pub. Date : 2002 Jun

PMID : 12079830






1 Functional Relationships(s)
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1 PPARalpha has been shown to bind and to be activated by leukotriene B4 and the hypolipidemic drugs of the fibrate class; PPARbeta/delta ligands are polyunsaturated fatty acids and prostaglandins; while prostaglandin J2 derivatives and the antidiabetic glitazones are, respectively, natural and synthetic ligands for PPARgamma. Prostaglandins peroxisome proliferator activated receptor gamma Homo sapiens