Title : Effects of angiotensin II infusion on renal excretion of purine bases and oxypurinol.

Pub. Date : 2002 Jul

PMID : 12077737






3 Functional Relationships(s)
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1 The fractional clearances of uric acid, xanthine, and oxypurinol were significantly decreased during angiotensin II infusion; however, that of hypoxanthine did not change. Uric Acid angiotensinogen Homo sapiens
2 The urinary excretion levels of uric acid, xanthine, and oxypurinol were also significantly decreased during angiotensin II infusion. Uric Acid angiotensinogen Homo sapiens
3 These results suggest that angiotensin II infusion affected the renal clearances of uric acid, xanthine, and oxypurinol through direct tubular transport and/or hemodynamic changes. Uric Acid angiotensinogen Homo sapiens