Pub. Date : 2002 May 23
PMID : 12069837
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of ERK by LPA proceeds via Gbetagamma-dependent activation of tyrosine kinases, including the epidermal growth factor (EGF) receptor and c-Src. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 2 | Further, LPA-induced ERK activation involves matrix metalloproteinases (MMPs), which cause the release of active EGFR ligands. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |