Pub. Date : 2002 May 23
PMID : 12069816
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the last several years, the epidermal growth factor (EGF) receptor has been recognized as a protein tyrosine kinase that plays a central role in mediating LPA-induced tyrosine phosphorylation and Erk MAP kinase activation. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |
| 2 | In this article, we review recent progress in the study of trans-regulation of EGF receptor by LPA and G protein-coupled receptors (GPCR) and discuss the gap in our knowledge of the mechanism by which LPA induces EGF receptor activation. | lysophosphatidic acid | epidermal growth factor receptor | Homo sapiens |