Title : Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1.

Pub. Date : 2002 Jun 10

PMID : 12058016






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Our data indicated that deficiencies in molecular chaperones Sis1 and Hsp104 inhibited seeding of polyQ aggregates, whereas ssa1, ssa2, and ydj1-151 mutations inhibited expansion of aggregates. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C