Title : Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways.

Pub. Date : 2002 Jun 14

PMID : 12056817






1 Functional Relationships(s)
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1 The results showed that a MEK1 inhibitor, PD98059, a p38MAPK inhibitor, SB202190, and a protein kinase C (PKC) inhibitor, Calphostin C, markedly decreased the IL-8 secretion from SK-N-MC (RET) cells at 24 h after GDNF stimulation. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one C-X-C motif chemokine ligand 8 Homo sapiens