Title : Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways.

Pub. Date : 2002 Jun 14

PMID : 12056817






5 Functional Relationships(s)
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1 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc ret proto-oncogene Homo sapiens
2 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc ret proto-oncogene Homo sapiens
3 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc ret proto-oncogene Homo sapiens
4 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc ret proto-oncogene Homo sapiens
5 To investigate which signaling pathways are responsible for IL-8 expression, we treated SK-N-MC (RET) cells with several kinase inhibitors before GDNF stimulation. sk-n-mc ret proto-oncogene Homo sapiens