Title : Transcriptional activation of the BNP gene by lipopolysaccharide is mediated through GATA elements in neonatal rat cardiac myocytes.

Pub. Date : 2002 Jun

PMID : 12054852






3 Functional Relationships(s)
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1 Transcriptional activation of the BNP gene by lipopolysaccharide is mediated through GATA elements in neonatal rat cardiac myocytes. gata natriuretic peptide B Rattus norvegicus
2 Mutation of the GATA sequence located at -95 and -84 abolished such an induction of BNP promoter activity. gata natriuretic peptide B Rattus norvegicus
3 These results indicate that LPS induces the BNP gene expression through a pathway involving CD14, Rac1, p38 MAPK and GATA elements. gata natriuretic peptide B Rattus norvegicus