Pub. Date : 2002 May 17
PMID : 12054510
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | H(2)O(2)-induced AP-1 activation and its effect on p21(WAF1/CIP1)-mediated G2/M arrest in a p53-deficient human lung cancer cell. | Hydrogen Peroxide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | PD98059, a specific inhibitor of MEK, diminished H(2)O(2)-induced phosphorylation of c-Jun and DNA binding activity of AP-1, decreased expression of p21(WAF1/CIP1), and released the cells from G2/M arrest. | Hydrogen Peroxide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | PD98059, a specific inhibitor of MEK, diminished H(2)O(2)-induced phosphorylation of c-Jun and DNA binding activity of AP-1, decreased expression of p21(WAF1/CIP1), and released the cells from G2/M arrest. | Hydrogen Peroxide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |