Title : Regulation of Smad3 expression in bleomycin-induced pulmonary fibrosis: a negative feedback loop of TGF-beta signaling.

Pub. Date : 2002 Jun 7

PMID : 12051713






2 Functional Relationships(s)
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1 Regulation of Smad3 expression in bleomycin-induced pulmonary fibrosis: a negative feedback loop of TGF-beta signaling. Bleomycin transforming growth factor beta 1 Homo sapiens
2 These studies provide direct evidence for a differential regulation of Smad3 expression that is distinct from that of Smad2 during bleomycin-induced pulmonary fibrosis and suggest a ligand-induced negative feedback loop that modulates cellular TGF-beta signaling. Bleomycin transforming growth factor beta 1 Homo sapiens