Pub. Date : 2002 Jun 7
PMID : 12051713
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of Smad3 expression in bleomycin-induced pulmonary fibrosis: a negative feedback loop of TGF-beta signaling. | Bleomycin | SMAD family member 3 | Homo sapiens |
| 2 | In this study, we investigated the expression of Smad2 and Smad3 in an in vivo animal model of lung fibrosis induced by bleomycin. | Bleomycin | SMAD family member 3 | Homo sapiens |
| 3 | We found that the expression of Smad3 was regulated in lungs during bleomycin-induced pulmonary fibrosis. | Bleomycin | SMAD family member 3 | Homo sapiens |
| 4 | The decline of Smad3 mRNA was evident at day three of post-bleomycin instillation and the expression of Smad3 continually decreased during the reparative phase of lung injury (days 8 and 12), whereas the expression of Smad2 showed little change after bleomycin administration. | Bleomycin | SMAD family member 3 | Homo sapiens |
| 5 | The decline of Smad3 mRNA was evident at day three of post-bleomycin instillation and the expression of Smad3 continually decreased during the reparative phase of lung injury (days 8 and 12), whereas the expression of Smad2 showed little change after bleomycin administration. | Bleomycin | SMAD family member 3 | Homo sapiens |