Pub. Date : 2002 Jun 11
PMID : 12048242
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calcium/calmodulin (Ca(2+)/CaM) binds to a site in the N-terminal region of CNGB1 subunits and inhibits the opening conformational change in CNGA1/CNGB1 channels. | cafestol palmitate | cyclic nucleotide gated channel subunit alpha 1 | Homo sapiens |
| 2 | These results suggest that Ca(2+)/CaM-dependent inhibition of rod channels is caused by the direct binding of Ca(2+)/CaM to a site in the N-terminal region in CNGB1, which disrupts the interaction between this region and a distal C-terminal region of CNGA1. | cafestol palmitate | cyclic nucleotide gated channel subunit alpha 1 | Homo sapiens |
| 3 | These results suggest that Ca(2+)/CaM-dependent inhibition of rod channels is caused by the direct binding of Ca(2+)/CaM to a site in the N-terminal region in CNGB1, which disrupts the interaction between this region and a distal C-terminal region of CNGA1. | cafestol palmitate | cyclic nucleotide gated channel subunit alpha 1 | Homo sapiens |