Title : Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells.

Pub. Date : 2002 Jun

PMID : 12040027






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 IL-1 increased SP-A expression in lung type II cells and had additive stimulatory effects with cAMP. Cyclic AMP interleukin 1 alpha Homo sapiens
2 Nuclear extracts from cAMP- or IL-1-treated type II cells manifested increased binding to NF-kappaB consensus and TBE probes; cAMP and IL-1 had additive effects. Cyclic AMP interleukin 1 alpha Homo sapiens
3 Nuclear extracts from cAMP- or IL-1-treated type II cells manifested increased binding to NF-kappaB consensus and TBE probes; cAMP and IL-1 had additive effects. Cyclic AMP interleukin 1 alpha Homo sapiens