Title : Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.

Pub. Date : 2002 Jun 15

PMID : 12036883






5 Functional Relationships(s)
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Protein Name
Organism
1 Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. Cyclosporine CD28 molecule Homo sapiens
2 The signaling event mediated by CD28 engagement has been proposed to have 2 components: one is sensitive to the immunosuppressive drug cyclosporin A (CsA), and the other one is CsA-resistant. Cyclosporine CD28 molecule Homo sapiens
3 The signaling event mediated by CD28 engagement has been proposed to have 2 components: one is sensitive to the immunosuppressive drug cyclosporin A (CsA), and the other one is CsA-resistant. Cyclosporine CD28 molecule Homo sapiens
4 The signaling event mediated by CD28 engagement has been proposed to have 2 components: one is sensitive to the immunosuppressive drug cyclosporin A (CsA), and the other one is CsA-resistant. Cyclosporine CD28 molecule Homo sapiens
5 Treatment with rapamycin blocked IL-2 production after activation of human peripheral blood T cells with phorbol ester (PMA) and anti-CD28 (CsA-resistant pathway), whereas this drug did not have any effect on PMA plus ionomycin stimulation (CsA-sensitive pathway). Cyclosporine CD28 molecule Homo sapiens