Pub. Date : 2002 May 28
PMID : 12032335
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A selective COX-2 inhibitor reduced platelet production of both PGE(2) and TXB(2) to a significantly greater extent in patients than in healthy subjects. | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | We conclude that both COX-isoforms contribute to prostanoid formation during human megakaryocytopoiesis and that COX-2-derived PGE(2) and TXA(2) may play an unrecognized role in inflammatory and hemostatic responses in clinical syndromes associated with high platelet turnover. | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |