Pub. Date : 2002 Jun 7
PMID : 12031494
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Downregulation of PGY1/MDR1 mRNA level in human KB cells by antisense oligonucleotide conjugates. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Downregulation of PGY1/MDR1 mRNA level in human KB cells by antisense oligonucleotide conjugates. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Three of the tested oligonucleotide conjugates specifically inhibited the expression of PGY1/MDR1 mRNA as monitored by the RT-PCR assay. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Three of the tested oligonucleotide conjugates specifically inhibited the expression of PGY1/MDR1 mRNA as monitored by the RT-PCR assay. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | The oligonucleotide conjugate targeted to the region (+178; +194) of the PGY1/MDR1 mRNA decreased level of this mRNA to 10% compared to the control. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | The oligonucleotide conjugate targeted to the region (+178; +194) of the PGY1/MDR1 mRNA decreased level of this mRNA to 10% compared to the control. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 7 | Nuclease-resistant analogs of oligonucleotide, complementary to this MDR1 mRNA region therefore, might be considered as a prototype compounds for development of gene-targeted therapeutic agents for overcoming the MDR phenotype caused by the overexpression of the PGY1/MDR1 gene. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 8 | Nuclease-resistant analogs of oligonucleotide, complementary to this MDR1 mRNA region therefore, might be considered as a prototype compounds for development of gene-targeted therapeutic agents for overcoming the MDR phenotype caused by the overexpression of the PGY1/MDR1 gene. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 9 | Nuclease-resistant analogs of oligonucleotide, complementary to this MDR1 mRNA region therefore, might be considered as a prototype compounds for development of gene-targeted therapeutic agents for overcoming the MDR phenotype caused by the overexpression of the PGY1/MDR1 gene. | Oligonucleotides | ATP binding cassette subfamily B member 1 | Homo sapiens |