Title : The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-kappaB activation, hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells.

Pub. Date : 2002 Jun

PMID : 12012007






1 Functional Relationships(s)
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1 In this study, we investigated particularly the effect of 100 microM NS-398 on p53 and p21 expression, caspase activities and nuclear factor-kappaB (NF-kappaB). N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide tumor protein p53 Homo sapiens