Title : Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-kappaB and AP-1.

Pub. Date : 2002 Jun

PMID : 12003776






3 Functional Relationships(s)
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1 The present study was undertaken to investigate the effects of treatment with the angiotensin-converting enzyme (ACE) inhibitor enalapril in a mouse model of pulmonary hypertension induced by bleomycin. Bleomycin angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus
2 The present study was undertaken to investigate the effects of treatment with the angiotensin-converting enzyme (ACE) inhibitor enalapril in a mouse model of pulmonary hypertension induced by bleomycin. Bleomycin angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus
3 These results suggest that ACE inhibitor treatment decreases lung injury and the development of pulmonary hypertension in bleomycin-treated mice. Bleomycin angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus