Title : Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction.

Pub. Date : 2002 Apr 23

PMID : 11997284






2 Functional Relationships(s)
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1 BACKGROUND: We tested the hypothesis that bicistronic cyclooxygenase-1 (COX-1)/prostacyclin synthase (PGIS) and COX-1 gene transfer reduce cerebral infarct volume by augmenting synthesis of protective prostaglandins. Prostaglandins prostaglandin-endoperoxide synthase 1 Rattus norvegicus
2 BACKGROUND: We tested the hypothesis that bicistronic cyclooxygenase-1 (COX-1)/prostacyclin synthase (PGIS) and COX-1 gene transfer reduce cerebral infarct volume by augmenting synthesis of protective prostaglandins. Prostaglandins prostaglandin-endoperoxide synthase 1 Rattus norvegicus