Title : Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c.

Pub. Date : 2002 Jun

PMID : 11997243






2 Functional Relationships(s)
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1 We inhibited ornithine decarboxylase, the first rate-limiting enzyme in polyamine synthesis, with alpha-difluoromethylornithine (DFMO) to deplete cells of polyamines. Eflornithine ornithine decarboxylase 1 Rattus norvegicus
2 We inhibited ornithine decarboxylase, the first rate-limiting enzyme in polyamine synthesis, with alpha-difluoromethylornithine (DFMO) to deplete cells of polyamines. Eflornithine ornithine decarboxylase 1 Rattus norvegicus