Title : Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines.

Pub. Date : 2002 Apr

PMID : 11995921






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 AKR1C1 efficiently reduced 3alpha,5alpha-THP, 5alpha-DHP and progesterone to their 20alpha-hydroxy metabolites, and slowly converted 5alpha-DHDOC to 3alpha,5alpha-THDOC. Progesterone aldo-keto reductase family 1 member C1 Homo sapiens