Title : Dexrazoxane has no impact on sensitivity of childhood leukemic blasts to daunorubicin.

Pub. Date : 2002 May

PMID : 11986942






4 Functional Relationships(s)
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1 The percentage of necrotic/apoptotic cells, as detected in cell cycle analysis and annexin V staining, was higher after exposure to DEX +/- DNR, when compared to respective samples not treated with DEX, in both cell lines but not in patient samples. Dexrazoxane annexin A5 Homo sapiens
2 Expression of annexin V induced by DEX in both cell lines was enlarged, regardless of the presence of DNR. Dexrazoxane annexin A5 Homo sapiens
3 This difference was not observed in patient samples, however, the number of cells expressing annexin V was higher after exposure to DEX +/- DNR in comparison to respective samples not treated with DEX. Dexrazoxane annexin A5 Homo sapiens
4 This difference was not observed in patient samples, however, the number of cells expressing annexin V was higher after exposure to DEX +/- DNR in comparison to respective samples not treated with DEX. Dexrazoxane annexin A5 Homo sapiens