Pub. Date : 2002 May 1
PMID : 11978772
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. | polyglutamine | heat shock protein family B (small) member 1 | Homo sapiens |
2 | In the present study, we identified heat shock protein 27 (HSP27) as a suppressor of poly(Q) mediated cell death, using a cellular model of HD. | polyglutamine | heat shock protein family B (small) member 1 | Homo sapiens |
3 | In the present study, we identified heat shock protein 27 (HSP27) as a suppressor of poly(Q) mediated cell death, using a cellular model of HD. | polyglutamine | heat shock protein family B (small) member 1 | Homo sapiens |
4 | We tested the hypotheses that HSP27 may reduce poly(Q)-mediated cell death either by binding cytochrome c and inhibiting the mitochondrial death pathway or by protecting against reactive oxygen species (ROS). | polyglutamine | heat shock protein family B (small) member 1 | Homo sapiens |