Title : Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro.

Pub. Date : 2002 May

PMID : 11973424






2 Functional Relationships(s)
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1 The widely prescribed drug desferrioxamine is a known activator of the hypoxia-inducible transcription factor 1 (HIF-1) and the subsequent transcription of erythropoietin. Deferoxamine erythropoietin Homo sapiens
2 Desferrioxamine induced HIF-1 DNA binding and transcription of erythropoietin in vivo, the temporal kinetics of which were congruent with tolerance induction. Deferoxamine erythropoietin Homo sapiens