Title : Acute effects of ACE inhibition on coronary endothelial dysfunction.

Pub. Date : 2000 Dec

PMID : 11967824






2 Functional Relationships(s)
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1 Treatment with the AT(1)-receptor antagonist losartan led to a slight improvement in microvascular endothelial function, but pre-treatment with losartan blunted the vascular effect of quinapril, suggesting that the combination of ACE inhibition and AT(1)-receptor antagonism may not exert a synergistic benefical impact on the coronary vasculature. Losartan angiotensin I converting enzyme Homo sapiens
2 Treatment with the AT(1)-receptor antagonist losartan led to a slight improvement in microvascular endothelial function, but pre-treatment with losartan blunted the vascular effect of quinapril, suggesting that the combination of ACE inhibition and AT(1)-receptor antagonism may not exert a synergistic benefical impact on the coronary vasculature. Losartan angiotensin I converting enzyme Homo sapiens