Title : Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis.

Pub. Date : 2002 Mar

PMID : 11966773






1 Functional Relationships(s)
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1 The inhibitors genistein (tyrosine kinase inhibitor) and calphostin C (inhibitor of protein kinase C) reduced significantly the IL-17-stimulated mRNA expression of IL-8, GRO-alpha and GRO-beta in SFC, whereas PD98059 (inhibitor of MEK-1/2) was without effect. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one C-X-C motif chemokine ligand 8 Homo sapiens