Title : Effects of high glucose on interleukin-6 production in human mesangial cells.

Pub. Date : 2002 Apr

PMID : 11961304






7 Functional Relationships(s)
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1 Effects of high glucose on interleukin-6 production in human mesangial cells. Glucose interleukin 6 Homo sapiens
2 Incubation of mesangial cells with high glucose (450 mg/dL) reduced the ratio of PCR products for IL-6 to beta-actin on densitometric results, while AGII (10(-7)M) increased it. Glucose interleukin 6 Homo sapiens
3 The IL-6 secretion in the supernatant was also increased by AGII and decreased by high glucose. Glucose interleukin 6 Homo sapiens
4 The IL-6 mRNA expression and IL-6 secretion in combination of high glucose and AGII were higher than those in high glucose and similar with those in control media. Glucose interleukin 6 Homo sapiens
5 The IL-6 mRNA expression and IL-6 secretion in combination of high glucose and AGII were higher than those in high glucose and similar with those in control media. Glucose interleukin 6 Homo sapiens
6 The IL-6 mRNA expression and IL-6 secretion in combination of high glucose and AGII were higher than those in high glucose and similar with those in control media. Glucose interleukin 6 Homo sapiens
7 The IL-6 production of mesangial cells in diabetic milieu may be complicated and depend on the local effects of high glucose and/or AGII. Glucose interleukin 6 Homo sapiens