Title : Prolonged hypobaric hypoxemia attenuates vasopressin secretion and renal response to osmostimulation in men.

Pub. Date : 2002 May

PMID : 11960941






1 Functional Relationships(s)
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1 In conclusion, chronic hypobaric hypoxemia 1) elevates the set point of plasma osmolality-to-plasma vasopressin relationship, possibly because of concurrent hypertension, thereby causing hypovolemia and hyperosmolality, and 2) blunts the natriuretic response to hypertonic volume expansion, possibly because of elevated circulating levels of norepinephrine and endothelin, reduced urodilatin synthesis, or attenuated inhibition of the renin system. Norepinephrine arginine vasopressin Homo sapiens