Title : [Distinct structural bases of the immunoregulatory and central analgesic effects of IFNalpha].

Pub. Date : 2000 Jun

PMID : 11956564






1 Functional Relationships(s)
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1 When the 129th Tyr residue of human IFNalpha was mutated to Ser, the immunoactivity of the mutant almost disappeared, while the strong analgesic activity still persisted, which could be blocked by naloxone. Serine interferon alpha 1 Homo sapiens