Title : Parathyroid hormone inhibits c-Jun N-terminal kinase activity in rat osteoblastic cells by a protein kinase A-dependent pathway.

Pub. Date : 2002 May

PMID : 11956171






1 Functional Relationships(s)
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1 We demonstrate that treatment of UMR 106-01 cells and rat calvarial osteoblasts with PTH (10(-8) M), N-terminal peptides of PTH that selectively activate PKA, or 8-bromo-cAMP (activates PKA) results in the inhibition of JNK activity from high basal levels. 8-Bromo Cyclic Adenosine Monophosphate parathyroid hormone Rattus norvegicus