Title : Erythromycin inhibits rhinovirus infection in cultured human tracheal epithelial cells.

Pub. Date : 2002 Apr 15

PMID : 11956054






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 Erythromycin reduced the supernatant RV14 titers, RV14 RNA, the susceptibility to RV14 infection, and the production of ICAM-1 and cytokines. Erythromycin intercellular adhesion molecule 1 Homo sapiens
2 These results suggest that erythromycin inhibits infection by the major RV subgroup by reducing ICAM-1 and infection by both RV subgroups by blocking the RV RNA entry into the endosomes. Erythromycin intercellular adhesion molecule 1 Homo sapiens
3 Erythromycin may also modulate airway inflammation by reducing the production of proinflammatory cytokines and ICAM-1 induced by RV infection. Erythromycin intercellular adhesion molecule 1 Homo sapiens