Title : Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage.

Pub. Date : 2002 Apr

PMID : 11953974






2 Functional Relationships(s)
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1 Although IL-1alpha alone did not significantly increase PGE(2) production, significant PGE(2) superinduction occurred in cartilage stimulated with IL-1alpha and the NOS2 inhibitor 1400W compared with stimulation with IL-1alpha alone in hypoxia, but not in normoxia. Prostaglandins E interleukin 1 alpha Homo sapiens
2 Although IL-1alpha alone did not significantly increase PGE(2) production, significant PGE(2) superinduction occurred in cartilage stimulated with IL-1alpha and the NOS2 inhibitor 1400W compared with stimulation with IL-1alpha alone in hypoxia, but not in normoxia. Prostaglandins E interleukin 1 alpha Homo sapiens