Title : Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy.

Pub. Date : 2002 Apr 22

PMID : 11953883






2 Functional Relationships(s)
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1 We have previously shown that butyrate is transported across the luminal membrane of the colonic epithelium via a monocarboxylate transporter, MCT1. Butyrates solute carrier family 16 member 1 Homo sapiens
2 Carcinoma samples displaying reduced levels of MCT1 were found to express the high affinity glucose transporter, GLUT1, suggesting that there is a switch from butyrate to glucose as an energy source in colonic epithelia during transition to malignancy. Butyrates solute carrier family 16 member 1 Homo sapiens