Title : Abrogation of the S phase DNA damage checkpoint results in S phase progression or premature mitosis depending on the concentration of 7-hydroxystaurosporine and the kinetics of Cdc25C activation.

Pub. Date : 2002 Jul 19

PMID : 11953432






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the p53 mutant cells, low concentrations of UCN-01 caused S phase cells to progress to G(2) before undergoing mitosis and death, whereas high concentrations caused rapid premature mitosis and death of S phase cells. 7-hydroxystaurosporine tumor protein p53 Homo sapiens