Title : Is ventilatory acclimatization to hypoxia a phenomenon that arises through mechanisms that have an intrinsic role in the regulation of ventilation at sea level?

Pub. Date : 2001

PMID : 11950148






3 Functional Relationships(s)
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1 The purpose of this article is to set out the hypothesis that arterial PO2 may play a significant role in the regulation of breathing at sea level. PO-2 S13 erythroblastosis (avian) oncogene homolog Homo sapiens
2 2) Although the ventilatory response to an acute variation in alveolar PO2 around sea-level values is feeble, studies at altitude have shown that over longer-time periods alveolar PO2 is a more powerful regulator of ventilation. PO-2 S13 erythroblastosis (avian) oncogene homolog Homo sapiens
3 3) Recent evidence suggests that mechanisms associated with ventilatory acclimatization to hypoxia are active at sea-level values for PO2, and indeed affect the acute ventilatory response to hypoxia. PO-2 S13 erythroblastosis (avian) oncogene homolog Homo sapiens