Pub. Date : 2002 Jun 21
PMID : 11940578
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To explore the importance of the c-Raf/MAPK kinase (MEK)/MAPK pathway, we stimulated adult feline cardiomyocytes with 12-O-tetradecanoylphorbol-13-acetate (TPA), insulin, or forskolin to activate PKC, phosphatidylinositol-3-OH kinase, or protein kinase A (PKA), respectively. | Tetradecanoylphorbol Acetate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |
| 2 | Dominant negative c-Raf expression or a MEK1/2 inhibitor (U0126) treatment showed a profound blocking effect only on the TPA-stimulated phosphorylation of S6K1 and mTOR. | Tetradecanoylphorbol Acetate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |