Title : Synthesis and biological evaluation of aroylguanidines related to amiloride as inhibitors of the human platelet Na(+)/H(+) exchanger.

Pub. Date : 2002 Jun

PMID : 11937337






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Our investigations demonstrated that the replacement of the pyrazine ring of amiloride by a pyridine or a phenyl ring improved the NHE inhibitory potency (phenyl >pyridine >pyrazine). Pyrazines solute carrier family 9 member C1 Homo sapiens
2 Our investigations demonstrated that the replacement of the pyrazine ring of amiloride by a pyridine or a phenyl ring improved the NHE inhibitory potency (phenyl >pyridine >pyrazine). Pyrazines solute carrier family 9 member C1 Homo sapiens