Title : Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.

Pub. Date : 2002 Apr

PMID : 11927623






1 Functional Relationships(s)
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1 In human apoA-I transgenic mice, treatment with the FXR agonist taurocholic acid strongly decreased serum concentrations and liver mRNA levels of human apoA-I, which was associated with reduced serum HDL levels. Taurocholic Acid nuclear receptor subfamily 1, group H, member 4 Mus musculus