Pub. Date : 2001 Dec
PMID : 11920914
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Peripheral site ligands accelerate inhibition of acetylcholinesterase by neutral organophosphates. | Organophosphates | acetylcholinesterase | Mus musculus |
| 2 | These observations suggest that peripheral site ligands are capable of allosterically affecting the conformation of residues in the choline binding site of AChE, thus optimizing the position of the leaving group of uncharged organophosphates during the inhibition reaction. | Organophosphates | acetylcholinesterase | Mus musculus |