Pub. Date : 2002 Jun 7
PMID : 11916978
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The phosphorylation state of Ser(183) in the cytoplasmic tail of syndecan-4 determines the binding affinity of the cytoplasmic tail to phosphatidylinositol 4,5-bisphosphate (PIP(2)), the capacity of the tail to multimerize, and its ability to activate protein kinase C (PKC) alpha. | Phosphatidylinositol 4,5-Diphosphate | syndecan 4 | Homo sapiens |
| 2 | Syndecan-4/PIP(2)-dependent PKCalpha activity was significantly increased in PKCdelta DN cells, while PKCdelta overexpression was accompanied by decreased PKCalpha activity. | Phosphatidylinositol 4,5-Diphosphate | syndecan 4 | Homo sapiens |