Title : Involvement of phosphatidylinositol-3-kinase in membrane ruffling induced by P-glycoprotein substrates in multidrug-resistant carcinoma cells.

Pub. Date : 2002 Mar 1

PMID : 11911848






1 Functional Relationships(s)
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1 Drugs transported by P-gp, vinblastine and trans-flupenthixol, increased membrane ruffling and PI-3-kinase activity in the MDR cell lines, MCF-7/AdrR and KBV-1, which overexpress P-gp. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens