Pub. Date : 2002 Mar 29
PMID : 11906162
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In 3T3-L1 adipocytes, we previously reported that glucosamine impairs insulin stimulation of glucose transport, which is accompanied by impaired insulin stimulation of serine/threonine kinase Akt. | Glucosamine | insulin | Homo sapiens |
| 2 | To examine the role of Akt in glucosamine-induced insulin resistance, we investigated time course for insulin stimulation of Akt activity and glucose transport during recovery from glucosamine-induced insulin resistance. | Glucosamine | insulin | Homo sapiens |
| 3 | After induction of insulin resistance by glucosamine, we washed cells to remove glucosamine and incubated them for various times. | Glucosamine | insulin | Homo sapiens |
| 4 | These data suggest that an Akt-independent mechanism is operative in glucosamine-induced insulin resistance and glucosamine impairs glucose transport stimulated by various stimuli involving and not involving Akt activation. | Glucosamine | insulin | Homo sapiens |