Pub. Date : 2002 Mar 19
PMID : 11904449
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Estradiol inhibits vascular cell adhesion molecule-1 (VCAM-1) expression, and expression of VCAM-1 is one of the early events in atherogenesis. | Estradiol | vascular cell adhesion molecule 1 | Homo sapiens |
| 2 | Estradiol inhibits vascular cell adhesion molecule-1 (VCAM-1) expression, and expression of VCAM-1 is one of the early events in atherogenesis. | Estradiol | vascular cell adhesion molecule 1 | Homo sapiens |
| 3 | Estradiol also attenuated VCAM-1 mRNA expression, but this action was not abolished in the presence of anastrozole, indicating that anastrozole itself did not modulate VCAM-1 mRNA expression. | Estradiol | vascular cell adhesion molecule 1 | Homo sapiens |
| 4 | In conclusion, testosterone inhibited VCAM-1 mRNA and protein expression in HUVEC by its conversion to estradiol via the enzyme aromatase present in the endothelial cells. | Estradiol | vascular cell adhesion molecule 1 | Homo sapiens |