Title : A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase.

Pub. Date : 2001

PMID : 11900310






2 Functional Relationships(s)
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1 Experimental evidence from the use of agents with enhanced selectivity for BuChE (cymserine, MF-8622) and ChE inhibitors such as rivastigmine, which have a dual inhibitory action on both AChE and BuChE, indicate potential therapeutic benefits of inhibiting both AChE and BuChE in AD and related dementias. Rivastigmine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Experimental evidence from the use of agents with enhanced selectivity for BuChE (cymserine, MF-8622) and ChE inhibitors such as rivastigmine, which have a dual inhibitory action on both AChE and BuChE, indicate potential therapeutic benefits of inhibiting both AChE and BuChE in AD and related dementias. Rivastigmine acetylcholinesterase (Cartwright blood group) Homo sapiens