Title : Donepezil hydrochloride: a treatment drug for Alzheimer's disease.

Pub. Date : 2001

PMID : 11893059






1 Functional Relationships(s)
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1 The earliest known AChE inhibitors, namely, physostigmine and tacrine, performed poorly in clinical trials (e.g., poor oral activity, brain penetration, and hepatotoxic liability). Physostigmine acetylcholinesterase (Cartwright blood group) Homo sapiens