Title : Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats.

Pub. Date : 2002 May

PMID : 11891877






2 Functional Relationships(s)
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1 Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats. Nicotine 4-aminobutyrate aminotransferase Rattus norvegicus
2 These results are the first to suggest that reversible inhibition of GABA transaminase may be useful in blocking cue-induced relapse to nicotine and cocaine. Nicotine 4-aminobutyrate aminotransferase Rattus norvegicus